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CIR1A Rabbit Polyclonal Antibody, 100ul Antibody Humanization PIGW acts in the third

SKU: 8972072314

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CIR1A Rabbit Polyclonal Antibody, 100ul Antibody Humanization PIGW acts in the thirdThis gene encodes a WD40 repeat containing protein that is localized to the nucleolus. Mutation of this gene causes North American Indian childhood cirrhosis, a severe intrahepatic cholestasis that results in transient neonatal jaundice, and progresses to periportal fibrosis and cirrhosis in childhood and adolescence. Alternative splicing results in multiple transcript variants.

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Description

PIGW acts in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol (Murakami et al

The encoded protein is comprised solely of a BAR domain which is predicted to form coiled-coil structures and proposed to mediate dimerization

Reduced expression and rearrangement of this gene have been detected in various cancers

histone lysine methyltransferase complex subunit) encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins

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CIR1A Rabbit Polyclonal Antibody, 100ul Antibody Humanization PIGW acts in the thirdThis gene encodes a WD40 repeat containing protein that is localized to the nucleolus. Mutation of this gene causes North American Indian childhood cirrhosis, a severe intrahepatic cholestasis that results in transient neonatal jaundice, and progresses to periportal fibrosis and cirrhosis in childhood and adolescence. Alternative splicing results in multiple transcript variants.

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