Oncogene TIM Polyclonal Antibody, 100ul Protein Modification This gene encodes a member

This gene encodes a member of the R-spondin family of proteins

The protein encoded by this gene is a membrane-associated GTP-ase which localizes to the plasma membrane and is related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) proteins

This protein can be phosphorylated by tyrosine kinases

which leads to a reduction in p53 levels and an increase in growth of the cancer cells

Other proteins containing the arm repeat are involved in development

Oncogene TIM Polyclonal Antibody, 100ul Protein Modification This gene encodes a memberRho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The protein encoded by ARHGEF5 (Rho guanine nucleotide exchange factor 5) may form a complex with G proteins and stimulate Rho dependent signals. This protein may be involved in the control of cytoskeletal organization.