CD58 Polyclonal Antibody, 100ul[BT-AP01884] Enzymes Mutations in this gene are

Mutations in this gene are associated with a variety of human cancers| including hereditary cancers such as Li-Fraumeni syndrome

They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens

The encoded protein interacts with several integrins and with heparan sulfate proteoglycan

IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes

and has been linked to primary microcephaly and Alzheimer's disease

CD58 Polyclonal Antibody, 100ul[BT-AP01884] Enzymes Mutations in this gene areCASP1 (caspase 1) encodes a protein which is a member of the cysteine aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. CASP1 was identified by its ability to proteolytically