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Survivin Polyclonal Antibody, 20ul[BT-AP14596] Diagnostic Probes & Oligos It also functions as an

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Survivin Polyclonal Antibody, 20ul[BT-AP14596] Diagnostic Probes & Oligos It also functions as anThis gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues.

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Description

It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell

Microdeletions in this gene are associated with contiguous ABCD1/DXS1375E deletion syndrome (CADDS)

An additional gene

Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta

Isoform 1 but not isoform 2 is activated through autoproteolytic processing

Survivin Polyclonal Antibody, 20ul[BT-AP14596] Diagnostic Probes & Oligos It also functions as anThis gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues.

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