SOS1 Polyclonal Antibody, 50ul Supplements The encoded protein binds to

The encoded protein binds to the initiator element (Inr) and E-box element in promoters and functions as a regulator of transcription

|PTM:TNF-alpha induces a caspase-mediated cleavage of p22 BID into a major p15 and minor p13 and p11 products

Pseudogenes associated with this gene are located on chromosomes 7 and 9

The encoded enzyme associates with AppBp1| an amyloid beta precursor protein binding protein| to form a heterodimer| and then the enzyme complex activates NEDD8| a ubiquitin-like protein| which regulates cell division| signaling and embryogenesis

such as the anti-cancer drugs cyclophosphamide and ifosphamide

SOS1 Polyclonal Antibody, 50ul Supplements The encoded protein binds toThis gene encodes a protein that is a guanine nucleotide exchange factor for RAS proteins, membrane proteins that bind guanine nucleotides and participate in signal transduction pathways. GTP binding activates and GTP hydrolysis inactivates RAS proteins. The product of this gene may regulate RAS proteins by facilitating the exchange of GTP for GDP. Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4.