EDEM2 Polyclonal Antibody, 100ul DNA Synthesis Mutations in this gene may

Mutations in this gene may be associated with type 2 diabetes in human patients

The 26S proteosome complex is required for ubiquitin-dependent protein degradation

and it apparently protects neurons against oxidative stress and cell death

Several related pseudogenes have also been identified

transcription activation and apoptosis

EDEM2 Polyclonal Antibody, 100ul DNA Synthesis Mutations in this gene mayIn the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins.