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CD6 Polyclonal Antibody, 100ul[BT-AP01719] Peptide Synthesis Mutations in this gene are

SKU: 8913296267

4.4
PLN123.75 PLN157.75

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CD6 Polyclonal Antibody, 100ul[BT-AP01719] Peptide Synthesis Mutations in this gene areThe protein encoded by CFLAR (CASP8 and FADD like apoptosis regulator) is a regulator of apoptosis and is structurally similar to caspase 8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase 8. Several transcript variants encoding different isoforms have been found for CFLAR, and partial evidence for several more variants exists.

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Description

Mutations in this gene are associated with dolichol kinase deficiency

interact with nucleic acids and have diverse functions

The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP

both early in development as well as in later stages

The edge of the wells protrude to prevent cross-contamination and to facilitate sealing

CD6 Polyclonal Antibody, 100ul[BT-AP01719] Peptide Synthesis Mutations in this gene areThe protein encoded by CFLAR (CASP8 and FADD like apoptosis regulator) is a regulator of apoptosis and is structurally similar to caspase 8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase 8. Several transcript variants encoding different isoforms have been found for CFLAR, and partial evidence for several more variants exists.

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