NF-1 Polyclonal Antibody, 100ul Mammalian Expression The protein encoded by this

The protein encoded by this gene contains a RING finger domain

Certain mutations in this gene resulting in a functionally inadequate enzyme are associated with a rare genetic disorder causing nonspherocytic hemolytic anemia

Gene Ontology (GO) annotations related to this gene include chromatin binding and protein complex binding

and the formation of metastases (PubMed: 16636290)

The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts to the trans-Golgi network through endosomes where a second autocatalytic event takes place and the Catalytic activity is acquired

NF-1 Polyclonal Antibody, 100ul Mammalian Expression The protein encoded by thisNFIA encodes a member of the NF1 (nuclear factor 1) family of transcription factors. Multiple transcript variants encoding different isoforms have been found for this gene.