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ARHGF Polyclonal Antibody, 50ul Protein Analysis These kelch-like repeats promote substrate

SKU: 88629654907

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ARHGF Polyclonal Antibody, 50ul Protein Analysis These kelch-like repeats promote substrateRho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. This gene encodes a protein that functions as a specific guanine nucleotide exchange factor for RhoA. It also interacts with ephrin A4 in vascular smooth muscle cells. Two alternatively spliced transcripts variants that encode the same protein have been found for this gene.

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Description

These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex

and is also associated with other pathological disorders

Surface Ig non-covalently associates with two other proteins

type 2 diabetes

The protein encoded by this gene plays a crucial role in B-cell development

ARHGF Polyclonal Antibody, 50ul Protein Analysis These kelch-like repeats promote substrateRho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. This gene encodes a protein that functions as a specific guanine nucleotide exchange factor for RhoA. It also interacts with ephrin A4 in vascular smooth muscle cells. Two alternatively spliced transcripts variants that encode the same protein have been found for this gene.

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