PLXB1 Polyclonal Antibody, 100ul Electrophoresis & Labeling suggesting that it may also

suggesting that it may also play an important role in cells undergoing rapid cell division

This cyclin binds both CDK2 and CDC2 kinases

Several alternatively spliced transcript variants of this gene have been described| but their biological validity has not been determined

Several transcript variants encoding different isoforms have been found for PPP1R12A

The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit

PLXB1 Polyclonal Antibody, 100ul Electrophoresis & Labeling suggesting that it may alsodisease: Overexpressed and constitutively tyrosine phosphorylated in colon, liver, pancreas and gastric carcinoma cell lines. Overexpression increases MET activation and promotes invasive growth.,Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.,PTM: Phosphorylated on tyrosine residues by ERBB2 and MET upon SEMA4D binding.,PTM: