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TBCB Polyclonal Antibody, 50ul Cell Labeling & Imaging subunit:Interacts with LIN7C

SKU: 88458739358

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TBCB Polyclonal Antibody, 50ul Cell Labeling & Imaging subunit:Interacts with LIN7CBinds to alpha tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.,PTM: Phosphorylation by PAK1 is required for normal function. Phosphorylated upon DNA damage, probably by ATM or ATR.,PTM: Ubiquitinated in the presence of GAN

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Description

subunit:Interacts with LIN7C

CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins (Liu et al

) reported to contain a tumor suppressor gene(s)

PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases

It is located in intracellular vesicles

TBCB Polyclonal Antibody, 50ul Cell Labeling & Imaging subunit:Interacts with LIN7CBinds to alpha tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth.,PTM: Phosphorylation by PAK1 is required for normal function. Phosphorylated upon DNA damage, probably by ATM or ATR.,PTM: Ubiquitinated in the presence of GAN

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