Tie-2(Phospho Tyr1108) Polyclonal Antibody, 50ul High Speed Micro-Centrifuges This protein can activate MAPK8

This protein can activate MAPK8 independently of the actin filament-binding domain| and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP

This protein is found to undergo cell cycle-dependent phosphorylation

It may be a critical substrate for p210(bcr/abl)| a chimeric protein whose presence is associated with CML

Ideal for use in scientific and laboratory settings

probably through an TIR-TIR domain interaction with TLR4

Tie-2(Phospho Tyr1108) Polyclonal Antibody, 50ul High Speed Micro-Centrifuges This protein can activate MAPK8This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin like domains, three epidermal growth factor (EGF) like domains and three fibronectin type III repeats. The ligand angiopoietin 1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated