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RAD1 Polyclonal Antibody, 100ul[BT-AP13499] Serological Pipets |PTM:Constitutively sumoylated by SUMO1| SUMO2

SKU: 87993890122

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RAD1 Polyclonal Antibody, 100ul[BT-AP13499] Serological Pipets |PTM:Constitutively sumoylated by SUMO1| SUMO2This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9 1 1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9 1 1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described.

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Description

|PTM:Constitutively sumoylated by SUMO1| SUMO2 and SUMO3

Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only two have been determined

a motif known to be involved in protein-DNA and protein-protein interactions

The apelin receptor is related to the angiotensin receptor

It interacts with MDM2 and enhances p53/TP53 ubiquitination

RAD1 Polyclonal Antibody, 100ul[BT-AP13499] Serological Pipets |PTM:Constitutively sumoylated by SUMO1| SUMO2This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9 1 1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9 1 1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described.

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