PDK1(Phospho Ser241) Polyclonal Antibody, 100ul Microbial Genome Editing Acetylated by CBP and deacetylated

Acetylated by CBP and deacetylated by SIRT1

alpha 4 contains the C-terminal G domain which distinguishes all alpha chains from the beta and gamma chains

The WW domains are essential for localization to nuclear speckles

An important paralog of this gene is HAP1

This protein has been shown to be involved in the assembly process of glucocorticoid receptor

PDK1(Phospho Ser241) Polyclonal Antibody, 100ul Microbial Genome Editing Acetylated by CBP and deacetylatedCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,Phosphorylates and activates not only PKB AKT, but also PKA, PKC zeta, RPS6KA1 and RPS6KB1. May play a general role in signaling processes and in development (By similarity). Isoform 3 is catalytically inactive.,PTM: Phosphorylated on tyrosine and serine threonine. Phosphorylation on Ser 241 in the activation loop is required for full activity. PDK1 itself can autophosphorylate Ser 241,