Paxillin(Phospho Ser178) Polyclonal Antibody, 100ul Stepper chromosomal aberrations involving this gene

chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors

Shb is a widely expressed protein that localizes to both the cell membrane and the cytoplasm and plays an important role in signal transduction

disease:Defects in BMP4 are the cause of microphthalmia syndromic type 6 (MCOPS6)

This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1

where the La motif and adjacent amino acids fold into an RNA recognition motif

Paxillin(Phospho Ser178) Polyclonal Antibody, 100ul Stepper chromosomal aberrations involving this geneThis gene encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID: 9054445).