Flt-1 Polyclonal Antibody, 20ul[BT-AP03280] Culture Tubes Alternative splicing of this gene

Alternative splicing of this gene results in two transcript variants that encode the same protein

Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP)

but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal

The yeast homolog is also essential for initiation of DNA replication as cell division occurs

This protein has a calculated MW ~97 kDa

Flt-1 Polyclonal Antibody, 20ul[BT-AP03280] Culture Tubes Alternative splicing of this geneFLT1 encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand binding region with seven immunoglobulin (Ig) like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. fms related tyrosine kinase 1 binds to VEGFR A, VEGFR B and placental growth factor and plays an important role in