PKR(Phospho Thr446) Polyclonal Antibody, 100ul Molecular Weight Markers ATP binding cassette subfamily D

ATP binding cassette subfamily D member 4 encoded by ABCD4 is a member of the superfamily of ATP-binding cassette (ABC) transporters

eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit

It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions

TPRA1 is a gene on chromosome 3q21

Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20

PKR(Phospho Thr446) Polyclonal Antibody, 100ul Molecular Weight Markers ATP binding cassette subfamily DThe protein encoded by this gene is a serine threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.