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PEA-15 Polyclonal Antibody, 100ul[BT-AP07045] Cell fragmentation and collection The protein (BMX non-receptor tyrosine

SKU: 86162460842

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PEA-15 Polyclonal Antibody, 100ul[BT-AP07045] Cell fragmentation and collection The protein (BMX non-receptor tyrosinePEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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Description

The protein (BMX non-receptor tyrosine kinase) contains a PH-like domain

Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity

Overexpression of PMEPA1 may play a role in multiple types of cancer

including regulation of iron homeostasis

The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT)

PEA-15 Polyclonal Antibody, 100ul[BT-AP07045] Cell fragmentation and collection The protein (BMX non-receptor tyrosinePEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants.

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