Vav Polyclonal Antibody, 50ul Drug Development and Evaluation The encoded protein may play

The encoded protein may play a role in apoptosis in a caspase-dependent manner

|induction:By T-cell activation

is regulated by cAMP and calcium levels and is dependent on the phosphorylation of SIKs by LKB1 (By similarity)

a dystonia-parkinsonism disorder

GO annotations related to this gene include signal transducer activity and G-protein beta-subunit binding

Vav Polyclonal Antibody, 50ul Drug Development and Evaluation The encoded protein may playVAV1 (vav guanine nucleotide exchange factor 1) is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T cell and B cell development and activation. The encoded protein has been identified as the specific binding