EGFR(Phospho Tyr1110) Polyclonal Antibody, 20ul ROS/Nitric Oxide Detection This protein plays a critical

This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis

Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis

and functions as a mediator of the anti-apoptotic signals from TNF receptors

Expertly designed for laboratory use

Ras is converted from the active GTP-bound state to the inactive GDP-bound state and no longer activates downstream pathways that regulate gene expression

EGFR(Phospho Tyr1110) Polyclonal Antibody, 20ul ROS/Nitric Oxide Detection This protein plays a criticalThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.