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Phospho-Akt1 (T72) Polyclonal Antibody, 100ul Gene Synthesis Mutations in this gene are

SKU: 85605139702

4.3
PLN123.75 PLN155.75

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Phospho-Akt1 (T72) Polyclonal Antibody, 100ul Gene Synthesis Mutations in this gene areThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy

The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Rad52

and ȁlight scattering”

and is up-regulated in hereditary hemochromatosis

Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton

Phospho-Akt1 (T72) Polyclonal Antibody, 100ul Gene Synthesis Mutations in this gene areThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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