TPP1 Polyclonal Antibody, 20ul miRNA / siRNA Synthesis and RNA splicing (Miranda et

and RNA splicing (Miranda et al

This protein has broad specificity and cleaves a variety of substrates

The encoded protein catalyzes formation of protein cross-links between glutamine and lysine residues| often resulting in stabilization of protein assemblies

transport at the Golgi

WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD)

TPP1 Polyclonal Antibody, 20ul miRNA / siRNA Synthesis and RNA splicing (Miranda etThis gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically inactive enzyme which is activated and auto proteolyzed upon acidification. Mutations in this gene result in late infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific