Kv1.1 potassium channel Polyclonal Antibody, 50ul[BT-AP10784] Insect Expression It is selectively expressed in

It is selectively expressed in reactive stromal fibroblasts of epithelial cancers

the encoded protein initiates signalling through the CARD9-Bcl10-Malt1 pathway

A similar protein in mouse is thought to play a role in regulating the structures of the nucleolus and centromere in neurons

chromosome 2 encodes over 1

Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers

Kv1.1 potassium channel Polyclonal Antibody, 50ul[BT-AP10784] Insect Expression It is selectively expressed inThis gene encodes a voltage gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1 S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N terminus of the channel is associated with beta subunits that can modify the inactivation properties of