FKB1A Polyclonal Antibody, 100ul Immunology The encoded protein regulates transcription

The encoded protein regulates transcription by binding to regulatory regions of various cellular and viral genes that maybe involved in growth| development and metastasis

while binding to the LCK SH2 domain occurs only upon TCR stimulation

The encoded protein is highly similar to the largest subunit of the Drosophila NURF (nucleosome remodeling factor) complex

A mutation in this gene was found in a family with Stickler syndrome

This gene shares its 5' exon with the overlapping gene

FKB1A Polyclonal Antibody, 100ul Immunology The encoded protein regulates transcriptionThe protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF beta receptor. It also interacts with multiple intracellular calcium