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HNF-4 Alpha/Gamma Polyclonal Antibody, 20ul[BT-AP04161] Centrifuge Tube (Bottle) This protein contains 7 transmembrane

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HNF-4 Alpha/Gamma Polyclonal Antibody, 20ul[BT-AP04161] Centrifuge Tube (Bottle) This protein contains 7 transmembraneHepatocyte nuclear factor 4 alpha encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal

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Description

This protein contains 7 transmembrane domains and conserved cysteine residues

The nuclear-encoded DNA pol γ is the only DNA polymerase required for the replication of the mitochondrial DNA

Alternative splicing occurs between a splice site from exon 5 of this gene to the 3' splice site upstream of the open reading frame (ORF) of the adjacent gene

This autosomal dominant disorder is characterized by abnormal water reabsorption by kidney tubules due

BTBD6 (BTB/POZ domain-containing protein 6)

HNF-4 Alpha/Gamma Polyclonal Antibody, 20ul[BT-AP04161] Centrifuge Tube (Bottle) This protein contains 7 transmembraneHepatocyte nuclear factor 4 alpha encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal

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