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MARCH8 induces the internalization of several membrane glycoproteins (Goto et al

Contactins mediate cell surface interactions during nervous system development

but lacks cytoplasmic domain

This protein contains a Bcl-2 homology 3 (BH3)-like motif

MCR Polyclonal Antibody, 100ul CellSafe™ Push the boundaries of knowledgeThis gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are