Mouse Dickkopf Related Protein 2, DKK2 ELISA Kit, 96T Enzymes Participates in bidirectional cell-cell contact

Participates in bidirectional cell-cell contact signaling between antigen presenting cells and lymphocytes

resulting from intergenic splicing between P2RY11 and an immediately upstream gene (PPAN

a protein kinase domain

limiting the entry of microbes through the epithelial barriers (PubMed: 19144317)

The protein encoded by this gene localizes to the principal piece of the sperm flagellum in association with the fibrous sheath and exhibits calcium-binding when phosphorylated during capacitation

Mouse Dickkopf Related Protein 2, DKK2 ELISA Kit, 96T Enzymes Participates in bidirectional cell-cell contactAntagonizes canonical Wnt signaling by inhibiting LRP5 6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5 6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone