c-Fos(Phospho Ser362) Polyclonal Antibody, 20ul Mini dry bath ADGRE1 encodes adhesion G protein-coupled

ADGRE1 encodes adhesion G protein-coupled receptor E1 that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus

and uses flavin adenine dinucleotide and folate as cofactors

This protein localizes to the endoplasmic reticulum and is thought to be the predominant enzyme responsible for epoxidation of endogenous arachidonic acid in cardiac tissue

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The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion

c-Fos(Phospho Ser362) Polyclonal Antibody, 20ul Mini dry bath ADGRE1 encodes adhesion G protein-coupledThe Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP 1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.