MARH7 Polyclonal Antibody, 20ul Antibody Humanization This copy of the gene

This copy of the gene is full-length and is in the telomeric duplicated region

This gene is highly expressed in organs involved in lipid metabolism| and may play a role in Zellweger syndrome| in which cells are deficient in peroxisomes and have impaired bile acid synthesis

Mutations and alternative splicing in TSG101 occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression

Disruption of this gene is associated with focal epilepsy and speech disorder with or without mental retardation

The human 5-HT1F receptor is closely related to the 5-ht1E receptor and its gene has been localized to chromosome 3 (3q11)

MARH7 Polyclonal Antibody, 20ul Antibody Humanization This copy of the geneMARCH7 is a member of the MARCH family of membrane bound E3 ubiquitin ligases (EC 6. 3. 2. 19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Bartee et al., 2004