NDUB6 Polyclonal Antibody, 50ul Cell Biology Defects in this gene are

Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC)

this protease hydrolyzes proteins within specialized neutrophil lysosomes

and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus

and may also inhibit osteoblast differentiation

and stable gene expression

NDUB6 Polyclonal Antibody, 50ul Cell Biology Defects in this gene areThe protein encoded by this gene is a subunit of the multisubunit NADH: ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Alternative splicing occurs