ANGP2 Polyclonal Antibody, 50ul Organelle Studies a MAM domain and a

a MAM domain and a C-terminal GPI-anchoring site

Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases

Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH

Members of this family form the core of a highly conserved tumor suppressor network

Interacts with CUL4B and DDB1

ANGP2 Polyclonal Antibody, 50ul Organelle Studies a MAM domain and aThe protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE 2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.