TNF-R2 Polyclonal Antibody, 50ul Bottle-Top Dispenser Pseudogenes corresponding to this gene

Pseudogenes corresponding to this gene are found on chromosomes 3p

as well as non-protein-coding variants

and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell

The protein encoded by this gene regulates the DNA damage response through several different signaling pathways

The encoded protein may be involved in the formation of long actin microspikes

TNF-R2 Polyclonal Antibody, 50ul Bottle-Top Dispenser Pseudogenes corresponding to this geneTumor necrosis factor receptor superfamily member 1B encoded by TNFRSF1B is a member of the TNF receptor superfamily. Tumor necrosis factor receptor superfamily member 1B and TNF receptor 1 form a heterocomplex that mediates the recruitment of two anti apoptotic proteins, c IAP1 and c IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF receptor signalling is unknown, however, c IAP1 is thought to potentiate TNF induced