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Flk-1 Polyclonal Antibody, 100ul[BT-AP03269] Nucleic Acid Amplification It is an imprinted gene|

SKU: 83116615619

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SEK123.75 SEK144.75

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Flk-1 Polyclonal Antibody, 100ul[BT-AP03269] Nucleic Acid Amplification It is an imprinted gene|VEGF R1 is one of the five receptor tyrosine kinases (RTKs) (Flt 1, KDR Flk 1, Flt 4, tie 1, and tek tie 2) whose expression is almost exclusively restricted to the endothelial cells. Tie 1 and tek tie 2 define a new class of RTKs containing two immunoglobulin like domains, three EGF homology domains and three fibronectin type III domains in their extracellular regions. Flt 1, KDR Flk 1 and Flt 4 are members of the class III subfamily of RTKs

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Description

It is an imprinted gene| expressed only from the paternal allele| and epigenetic changes at this locus are associated with Wilms tumour| Beckwith-Wiedemann syndrome| rhabdomyosarcoma| and Silver-Russell syndrome

Encoded by a gene that maps to human chromosome 7q34

5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling

The mouse ortholog of this gene is specifically expressed in germ cells at the round spermatid stages during spermatogenesis and| when overexpressed| induces apoptosis

Ntm) family of immunoglobulin (Ig) domain-containing glycosylphosphatidylinositol (GPI)-anchored cell adhesion molecules

Flk-1 Polyclonal Antibody, 100ul[BT-AP03269] Nucleic Acid Amplification It is an imprinted gene|VEGF R1 is one of the five receptor tyrosine kinases (RTKs) (Flt 1, KDR Flk 1, Flt 4, tie 1, and tek tie 2) whose expression is almost exclusively restricted to the endothelial cells. Tie 1 and tek tie 2 define a new class of RTKs containing two immunoglobulin like domains, three EGF homology domains and three fibronectin type III domains in their extracellular regions. Flt 1, KDR Flk 1 and Flt 4 are members of the class III subfamily of RTKs

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