EMR2 Polyclonal Antibody, 50ul[BT-AP02941] Sample Library Tubes The encoded protein functions as

The encoded protein functions as both a DNA and RNA binding protein and has been implicated in numerous cellular processes including regulation of transcription and translation

Defects in PEX3 are a cause Zellweger syndrome (ZWS)

Mutations within this gene have been associated with Usher syndrome type IIa and retinitis pigmentosa

which have been implicated in the regulation of cytoskeletal dynamics

This gene may also play a role in tumor progression

EMR2 Polyclonal Antibody, 50ul[BT-AP02941] Sample Library Tubes The encoded protein functions asADGRE2 encodes a member of the class B seven span transmembrane (TM7) subfamily of G protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N terminal epidermal growth factor like domains coupled to a TM7 domain via a mucin like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell cell adhesion through interaction with chondroitin sulfate