CD58 Polyclonal Antibody, 100ul[BT-AP01637] Micro Centrifuge Tubes Alternative splicing leads to variants

Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region

|tissue specificity:Expressed in a number of tissues including heart| liver and prostate

but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal

In the brain this peptide may be responsible for the effects of stress on appetite

Members of the LY6 superfamily typically contain 70 to 80 amino acids| including 8 to 10 cysteines

CD58 Polyclonal Antibody, 100ul[BT-AP01637] Micro Centrifuge Tubes Alternative splicing leads to variantsThe cyclin dependent kinase 7 encoded by CDK7 is a member of the cyclin dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT2, which functions as a Cdk activating kinase (CAK). It is an essential component of