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HECW1 Polyclonal Antibody, 100ul Pipette Micro Tips This isozyme is highly expressed

SKU: 82784576978

4.8
EUR123.75 EUR158.75

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HECW1 Polyclonal Antibody, 100ul Pipette Micro Tips This isozyme is highly expressedE3 ubiquitin protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.,pathway: Protein modification; protein ubiquitination.,Contains 1 C2 domain.,Contains 1 HECT (E6AP type E3 ubiquitin protein ligase) domain.,Contains 2 WW

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Description

This isozyme is highly expressed in brain| and preferentially utilizes myristate| arachidonate| and eicosapentaenoate as substrates

plays a role in inflammatory responses through binding to the receptors CCR1

a process which occurs normally during development but also during metastasis

This caspase is able to cleave and activate its own precursor protein

13/16×100mm blood

HECW1 Polyclonal Antibody, 100ul Pipette Micro Tips This isozyme is highly expressedE3 ubiquitin protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.,pathway: Protein modification; protein ubiquitination.,Contains 1 C2 domain.,Contains 1 HECT (E6AP type E3 ubiquitin protein ligase) domain.,Contains 2 WW

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