MOAP1 Polyclonal Antibody, 50ul Proteases A mutation in this gene

A mutation in this gene has been reported to be associated with hereditary spastic paraplegia| however the pathogenicity of the mutation| which may simply represent a polymorphism| is unclear

Members of this family are secreted or membrane-anchored proteins mainly found in cells associated with the immune system

This gene encodes a member of the group 2 decarboxylase family

This gene has a related pseudogene| which is also present on chromosome 6

This gene encodes a protein that is likely to function in progression of meiosis

MOAP1 Polyclonal Antibody, 50ul Proteases A mutation in this geneThe protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl 2 homology 3 (BH3) like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to mediate caspase dependent apoptosis.