Phospho-Akt (S124) Polyclonal Antibody, 20ul Multiplex Immunoassays Most PSGs have an arg-gly-asp

Most PSGs have an arg-gly-asp (RGD) motif

but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues

this protein interacts with and phosphorylates BRCA1

May recognize and hydrolyze the peptide bond at the C-terminal Gly of ubiquitin

colon cancer and breast cancer

Phospho-Akt (S124) Polyclonal Antibody, 20ul Multiplex Immunoassays Most PSGs have an arg-gly-aspThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a