JAK3 Polyclonal Antibody, 100ul Glassware and White)

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The encoded protein plays a role in the early secretory pathway as a heterodimer with zinc transporter 6| and may also regulate zinc sequestration into secretory granules of pancreatic beta cells

TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB

resulting in several non-synonymous codon differences among individuals of different genetic backgrounds

ROBO family

JAK3 Polyclonal Antibody, 100ul Glassware and White)The protein encoded by JAK3 is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).