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Rb(Phospho Ser780) Polyclonal Antibody, 100ul Molecular Biologyn Various versions of each of

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Rb(Phospho Ser780) Polyclonal Antibody, 100ul Molecular Biologyn Various versions of each ofThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

Various versions of each of these subunits exist

laminin-11 (laminin-521) and laminin-15 (laminin-523)

resulting in hybrid cells that can generate both antibodies and proliferate indefinitely

ICAMs 1-3 (intercellular adhesion molecules 1 through 3)

The protein encoded by this gene is a member of the tectonin beta-propeller repeat-containing (TECPR) family| and contains both TECPR and tryptophan-aspartic acid repeat (WD repeat) domains

Rb(Phospho Ser780) Polyclonal Antibody, 100ul Molecular Biologyn Various versions of each ofThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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