Tuberin(Phospho Ser939) Polyclonal Antibody, 50ul Bottle-Top Dispenser Belongs to the PAR6 family

Belongs to the PAR6 family

This gene is part of a cluster of MMP genes on chromosome 11

SEPT6 encodes four transcript variants encoding three distinct isoforms

1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway

Tuberin(Phospho Ser939) Polyclonal Antibody, 50ul Bottle-Top Dispenser Belongs to the PAR6 familyMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.