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SNPH Polyclonal Antibody, 50ul Peptide Synthesis ATG12 is the human homolog

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SNPH Polyclonal Antibody, 50ul Peptide Synthesis ATG12 is the human homologSyntaxin 1, synaptobrevin VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane associated and inhibits SNARE complex formation by binding free syntaxin 1. Expression of this gene appears to be brain specific. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Description

ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al

which forms a complex with CDK4 or CDK6

The product of ETV6 contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins

Certain mutations in this gene cause butterfly-shaped pigment dystrophy

Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response

SNPH Polyclonal Antibody, 50ul Peptide Synthesis ATG12 is the human homologSyntaxin 1, synaptobrevin VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane associated and inhibits SNARE complex formation by binding free syntaxin 1. Expression of this gene appears to be brain specific. Alternative splicing results in multiple transcript variants encoding different isoforms.

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