TRY6 Rabbit Polyclonal Antibody, 100ul Reservoirs |PTM:Phosphorylated on tyrosines by ZAP-70

|PTM:Phosphorylated on tyrosines by ZAP-70 upon TCR activation| or by SYK upon other immunoreceptor activation

The protein encoded by this gene catalyzes the formation of inositol 1|4|5-trisphosphate and diacylglycerol from phosphatidylinositol 4|5-bisphosphate

In addition to forming homodimers

Gene Ontology (GO) annotations related to this gene include thrombin receptor activity

and regulate CD2-triggered T lymphocyte activation

TRY6 Rabbit Polyclonal Antibody, 100ul Reservoirs |PTM:Phosphorylated on tyrosines by ZAP-70Although this locus appears to encode a protein similar to trypsinogen the locus is thought to be a transcribed pseudogene. ESTs support its transcription but expression of its predicted protein has not been observed. Its predicted protein sequence differs significantly from the known functional trypsinogens including a different amino acid at the conserved residue 122 which is important for autolysis. This pseudogene and several other trypsinogen