HNF-1Beta Polyclonal Antibody, 100ul Centrifuges This gene is a member

This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation

Seems to negatively regulate apoptosis by promoting FADD phosphorylation

It plays a negative regulatory role in the Ras-Raf1-MAPK pathway

UBB consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence

This gene undergoes extensive alternative splicing to generate multiple isoforms| but the full-length nature of some of these variants has not been determined

HNF-1Beta Polyclonal Antibody, 100ul Centrifuges This gene is a memberHNF1B encodes a member of the homeodomain containing superfamily of transcription factors. Hepatocyte nuclear factor 1 beta binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1 alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin dependent diabetes