FAF1 Polyclonal Antibody, 20ul[BT-AP03131] Thermal Control FEV is fused to the

FEV is fused to the Ewing sarcoma (EWS) gene following chromosome translocations

These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana

The protein encoded by this gene is another member of the angiopoietin family that is widely expressed in adult tissues with mRNA levels highest in highly vascularized tissues

Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation

It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure

FAF1 Polyclonal Antibody, 20ul[BT-AP03131] Thermal Control FEV is fused to theInteraction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. FAS associated factor 1 encoded by FAF1 binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by this gene requires a ubiquitin like domain but not the FAS binding domain.