NTCP2 Rabbit Polyclonal Antibody, 50ul Polyclonal Antibody Preparation Contains 4 C3H1-type zinc fingers

Contains 4 C3H1-type zinc fingers

Mutations in KAL1 cause the X-linked Kallmann syndrome

Binds to F-actin but not to RNA

Family members play essential roles in innate immune response to a wide range of pathogenic organisms| tissue damage and other cellular stresses

This protein may also play a role in inhibiting viral replication

NTCP2 Rabbit Polyclonal Antibody, 50ul Polyclonal Antibody Preparation Contains 4 C3H1-type zinc fingersThis gene encodes a sodium bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines