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EGFR(Phospho Tyr869) Polyclonal Antibody, 100ul Culture Media Alternative splicing of this gene

SKU: 80337735451

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EGFR(Phospho Tyr869) Polyclonal Antibody, 100ul Culture Media Alternative splicing of this geneThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

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Description

Alternative splicing of this gene results in two transcript variants

Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses

Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA

TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki| 2006)

This protein binds F-actin| and also interacts with 5-lipoxygenase| which is the first committed enzyme in leukotriene biosynthesis

EGFR(Phospho Tyr869) Polyclonal Antibody, 100ul Culture Media Alternative splicing of this geneThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

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