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Frizzled-9 Polyclonal Antibody, 100ul[BT-AP03370] Protein Analysis Two forms of tryptophanyl-tRNA synthetase

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Frizzled-9 Polyclonal Antibody, 100ul[BT-AP03370] Protein Analysis Two forms of tryptophanyl-tRNA synthetaseMembers of the frizzled gene family encode 7 transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene (frizzled class receptor 9) is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney.

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Description

Two forms of tryptophanyl-tRNA synthetase exist

Epsin 2 is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery

Has a two domain structure: the G-domain binds GTP

The protein encoded by this gene regulates actin dynamics through interaction with Ena/Vasodilator proteins as well as direct binding to filamentous actin to regulate actin network assembly

The encoded protein stabilizes the ORC and therefore aids in DNA replication

Frizzled-9 Polyclonal Antibody, 100ul[BT-AP03370] Protein Analysis Two forms of tryptophanyl-tRNA synthetaseMembers of the frizzled gene family encode 7 transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene (frizzled class receptor 9) is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney.

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