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Neuregulin-3 Polyclonal Antibody, 100ul PCR Series and viral semaphorins may modulate

SKU: 79018239593

4.3
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Neuregulin-3 Polyclonal Antibody, 100ul PCR Series and viral semaphorins may modulateNRG3 (neuregulin 3) is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to

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Description

and viral semaphorins may modulate the immune response by binding to this receptor

The encoded enzyme is a retinoid target that triggers promyelocytic leukemia (PML)/retinoic acid receptor alpha (RARalpha) degradation and apoptosis in acute promyelocytic leukemia

It may play a role in tumor cell metastasis

p53 and BRCA1

Fusion of the N-terminus of this protein with the truncated C-terminus of the RET gene product has been shown to result in production of the ret transforming protein

Neuregulin-3 Polyclonal Antibody, 100ul PCR Series and viral semaphorins may modulateNRG3 (neuregulin 3) is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to

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