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JAM-B Polyclonal Antibody, 50ul Proteases Alternatively spliced transcript variants have

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JAM-B Polyclonal Antibody, 50ul Proteases Alternatively spliced transcript variants haveJAM2 belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. Junctional adhesion molecule B encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript

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Description

Alternatively spliced transcript variants have been described| but their biological validity has not been determined

This protease degrades soluble and insoluble elastin

It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes

Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome

It has an N-terminal short-chain dehydrogenase domain with a cofactor binding site

JAM-B Polyclonal Antibody, 50ul Proteases Alternatively spliced transcript variants haveJAM2 belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. Junctional adhesion molecule B encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript

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